• Body Size at Different Ages and Risk of 6 Cancers: A Mendelian Randomization and Prospective Cohort Study 

      Mariosa, Daniela; Smith-Byrne, Karl; Richardson, Tom G.; Ferrari, Pietro; Gunter, Marc J.; Papadimitriou, Nikos; Murphy, Neil; Christakoudi, Sofia; Tsilidis, Konstantinos K.; Riboli, Elio; Muller, David; Purdue, Mark P.; Chanock, Stephen J.; Hung, Rayjean J.; Amos, Christopher I.; O'Mara, Tracy A.; Amiano, Pilar; Pasanisi, Fabrizio; Rodriguez-Barranco, Miguel; Krogh, Vittorio; Tjønneland, Anne; Halkjær, Jytte; Perez-Cornago, Aurora; Chirlaque, María-Dolores; Skeie, Guri; Rylander, Charlotta; Borch, Kristin Benjaminsen; Aune, Dagfinn; Heath, Alicia K.; Ward, Heather A.; Schulze, Matthias; Bonet, Catalina; Weiderpass, Elisabete; Davey Smith, George; Brennan, Paul; Johansson, Mattias (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-19)
      It is unclear if body weight in early life affects cancer risk independently of adult body weight. To investigate this question for 6 obesity-related cancers, we performed univariable and multivariable analyses using 1) Mendelian randomization (MR) analysis and 2) longitudinal analyses in prospective cohorts. Both the MR and longitudinal analyses indicated that larger early life body size was ...
    • Ultra-processed foods, adiposity and risk of head and neck cancer and oesophageal adenocarcinoma in the European Prospective Investigation into Cancer and Nutrition study: a mediation analysis 

      Morales-Berstein, Fernanda; Biessy, Carine; Viallon, Vivian; Goncalves-Soares, Ana; Casagrande, Corinne; Hémon, Bertrand; Kliemann, Nathalie; Cairat, Manon; Blanco Lopez, Jessica; Al Nahas, Aline; Chang, Kiara; Vamos, Eszter; Rauber, Fernanda; Bertazzi Levy, Renata; Barbosa Cunha, Diana; Jakszyn, Paula; Ferrari, Pietro; Vineis, Paolo; Masala, Giovanna; Catalano, Alberto; Sonestedt, Emily; Borné, Yan; Katzke, Verena; Bajracharya, Rashmita; Agnoli, Claudia; Guevara, Marcela; Heath, Alicia; Radoï, Loredana; Mancini, Francesca; Weiderpass Vainio, Elisabete; Huerta, José María; Sánchez, María-José; Tjønneland, Anne; Kyrø, Cecilie; Schulze, Matthias B.; Skeie, Guri; Lukic, Marko; Braaten, Tonje Bjørndal; Gunter, Marc; Millett, Christopher; Agudo, Antonio; Brennan, Paul; Borges, M. Carolina; Richmond, Rebecca C.; Richardson, Tom G.; Davey Smith, George; Relton, Caroline L.; Huybrechts, Inge (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-11-22)
      Purpose - To investigate the role of adiposity in the associations between ultra-processed food (UPF) consumption and head and neck cancer (HNC) and oesophageal adenocarcinoma (OAC) in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort.<p> <p>Methods - Our study included 450,111 EPIC participants. We used Cox regressions to investigate the associations between the ...